Tag Archives: site-specific

Memoir 36 – The Geological Record of Neoproterozoic Glaciations

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Memoir 36 – The Geological Record of Neoproterozoic Glaciations (Geological Society Memoir) by E Arnaud and G P Halverson
English | 2011-10-15 | ISBN: 1862393346 | PDF | 752 pages | 32 MB

Memoir 36 – The Geological Record of Neoproterozoic Glaciations
In recent years, interest in Neoproterozoic glaciations has grown as their pivotal role in Earth system evolution has become increasingly clear. One of the main goals of the IGCP Project number 512 was to produce a synthesis of newly available information on Neoproterozoic successions worldwide similar in format to Hambrey & Harlands (1981) Earths pre Pleistocene Glacial Record. This Memoir therefore consists of a series of overview chapters followed by site-specific chapters. The overview chapters cover key topics including the history of research on Neoproterozoic glaciations, identification of glacial deposits, chemostratigraphic techniques and datasets, palaeomagnetism, biostratigraphy, geochronology and climate modelling. The site specific chapters for 60 successions worldwide include reviews of the history of research on these rocks and up-to-date syntheses of the structural framework, tectonic setting, palaeomagnetic and geochronological constraints, physical, biological, and chemical stratigraphy, and descriptions of the glaciogenic and associated strata, including economic deposits.
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High-Field EPR Spectroscopy on Proteins and their Model Systems

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Klaus Möbius, Anton Savitsky, M J Davies, "High-Field EPR Spectroscopy on Proteins and their Model Systems: Characterization of Transient Paramagnetic States"
2009 | pages: 391 | ISBN: 0854043683 | PDF | 7,2 mb

High-Field EPR Spectroscopy on Proteins and their Model Systems
Understanding the major factors determining the specificity of transmembrane transfer processes in proteins is currently a hot topic in molecular bio-science. Advanced electron paramagnetic resonance (EPR) at high magnetic fields is a powerful technique for characterizing the transient states of proteins in action on biologically relevant time scales. This book offers a comprehensive overview of experimental techniques in, and paradigmatic examples of, the application of high-field EPR spectroscopy in biology and chemistry. It focuses on the use of the technique in conjunction with site-specific mutation strategies and advanced quantum-chemical computation methods to reveal protein structure and dynamics. This yields new insights into biological processes at the atomic and molecular level. The theoretical and instrumental background of high-field EPR is described and examples of paradigmatic protein systems, such as photosynthesis, are discussed in the light of recent investigations. Aspects of structure-dynamics-function relations that are revealed by studying site-specific mutants are highlighted, thereby combining high-field EPR with genetic engineering techniques. The information obtained complements that obtained from protein crystallography, solid-state NMR, infrared and optical spectroscopy. The book documents both background knowledge and results of the latest research in the field. Unique features include comparisons of information content of EPR, ENDOR, Triple resonance, ESEEM and PELDOR taken at different microwave frequencies and magnetic fields. Coherent treatment of the subject by the leading Berlin high-field EPR laboratory covers the theoretical background as well as state-of-art research both in terms of instrumentation and application to biological systems. Finally, the book provides an outlook to future developments and references for further reading. High-Field EPR Spectroscopy on Proteins in Action is essential reading for scientists, professionals, academics and post graduate students working in this field.
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The Mouse Nervous System

Charles Watson, George Paxinos, Luis Puelles – The Mouse Nervous System
Published: 2011-12-12 | ISBN: 0123694973 | PDF | 814 pages | 97 MB

The Mouse Nervous System provides a comprehensive account of the central nervous system of the mouse. The book is aimed at molecular biologists who need a book that introduces them to the anatomy of the mouse brain and spinal cord, but also takes them into the relevant details of development and organization of the area they have chosen to study. The Mouse Nervous System offers a wealth of new information for experienced anatomists who work on mice. The book serves as a valuable resource for researchers and graduate students in neuroscience.
Systematic consideration of the anatomy and connections of all regions of the brain and spinal cord by the authors of the most cited rodent brain atlases
A major section (12 chapters) on functional systems related to motor control, sensation, and behavioral and emotional states
A detailed analysis of gene expression during development of the forebrain by Luis Puelles, the leading researcher in this area
Full coverage of the role of gene expression during development and the new field of genetic neuroanatomy using site-specific recombinases
Examples of the use of mouse models in the study of neurological illness

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